Catholic Commentary
The Prayer of Sanctification and God's Faithfulness
23May the God of peace himself sanctify you completely. May your whole spirit, soul, and body be preserved blameless at the coming of our Lord Jesus Christ.24He who calls you is faithful, who will also do it.
1 Thessalonians 5:23–24 contains Paul's prayer that God will sanctify the Thessalonians completely—spirit, soul, and body—and preserve them blameless until Christ's return, grounded in the assurance that God is faithful and will accomplish what he has called them to. The passage emphasizes that holiness originates from God's action rather than human effort, and that the promise of completion rests on divine character rather than explicable mechanism.
God doesn't help you become holy—he makes you holy himself, and he keeps what he promises.
1 Thessalonians 5:23 — "May the God of peace himself sanctify you completely"
Paul opens with a striking divine title: ho Theos tēs eirēnēs — "the God of peace." This is not decorative. Throughout 1 Thessalonians, the community has been anxious about persecution (2:14–16), about the fate of their dead (4:13–18), and about the timing of the Day of the Lord (5:1–11). The God who now prays over them is precisely the One who makes whole what is broken and reconciles what is estranged — the author of shalom in its fullest Hebrew sense. Peace, not wrath, is the ground of sanctification.
The verb hagiasai (sanctify) is an aorist optative — a form expressing a wish or prayer. Its subject is emphatically God himself (autos): Paul does not say "may you sanctify yourselves" but "may he sanctify you." This is the first key theological move: holiness has a divine, not a human, origin. The adverb holoteleis — "completely," "through and through," "to the very end" — appears nowhere else in the Greek New Testament. Paul is coining or deploying a rare intensive to insist on totality. Nothing in the person is left outside the scope of sanctification.
"May your whole spirit, soul, and body be preserved blameless"
Paul then unpacks what "completely" means through a tripartite anthropology: pneuma (spirit), psychē (soul), and sōma (body). The order is unusual — elsewhere Paul speaks of body and spirit (1 Cor 6:20; 7:34) or body, soul, and spirit in various combinations — but here the sequence likely moves from the deepest center of the person outward to the most visible and vulnerable dimension. The pneuma is the capacity for relationship with God, the innermost point of contact with the Holy Spirit; the psychē is the animating principle of personal identity and emotion; the sōma is the concrete, historical, mortal body that will one day be raised.
The verb tēreō — "preserved," "kept" — adds a dimension of continuity: sanctification is not only an event but a sustained state of being guarded. The goal is that this whole person arrive at the coming (parousia) of our Lord Jesus Christ in the condition of amemptōs — "blameless," "without reproach." This is eschatological language: Paul envisions the human person standing before Christ at his return intact and holy. The body is explicitly included, which has enormous consequences for Catholic anthropology and its rejection of any body-soul dualism that would treat the flesh as irrelevant to salvation.
1 Thessalonians 5:24 — "He who calls you is faithful, who will also do it"
This single sentence is the theological anchor of the entire passage. The present participle ho kalōn ("the one who calls") indicates ongoing call — God's vocation is not a past event but a present, active summons. The adjective pistos ("faithful") links God's character to His ability to complete the project He has begun: because He is faithful, the audacious prayer of verse 23 is not wishful thinking but confident hope. The final kai poiēsei — "he will also do it" — is a simple future of astonishing brevity. Paul does not explain how. He simply asserts the certainty of divine completion.
This two-verse unit thus has the structure of a liturgical blessing followed by a creedal affirmation: petition (v. 23) and confessional grounding (v. 24). The movement from prayer to profession mirrors the deep logic of Catholic liturgy itself.
Catholic tradition reads these verses as a concentrated scriptural foundation for the doctrine of sanctification and its inseparability from both eschatology and anthropology.
On the Tripartite Anthropology: The Fathers were not uniformly settled on whether Paul's pneuma-psychē-sōma scheme implies three distinct substances. Origen and certain Alexandrians developed a trichotomist reading, while Augustine tended toward a bipartite view (spirit/soul as two aspects of the same immaterial principle). The Catechism of the Catholic Church (§362–368) follows a nuanced anthropological vision: the human person is a unity of body and soul, while acknowledging that "soul" and "spirit" can be used interchangeably in Scripture or can denote distinct capacities. What is non-negotiable is the dignity of the body: "The human body shares in the dignity of 'the image of God'" (CCC §364). Paul's explicit inclusion of the body as an object of sanctification directly supports the Church's consistent affirmation that matter is not an obstacle to holiness but its arena.
On Sanctification as Divine Work: The Council of Trent (Session VI, Decree on Justification) insists that while human cooperation is real, the initium — the beginning — of justification and sanctification is always God's grace, not human merit. Paul's emphatic autos ("himself") anticipates precisely this: God is not merely assisting human self-improvement but is the primary agent of transformation. St. Thomas Aquinas, commenting on the Pauline corpus, observes that sanctification is ordered to an end — the Parousia — and that God's faithfulness is the guarantee that the means (grace) will be proportionate to the end (glory). This resonates with the Catechism's teaching that "the grace of the Holy Spirit has the power to justify us, that is, to cleanse us from our sins and to communicate to us 'the righteousness of God through faith in Jesus Christ'" (CCC §1987).
On God's Faithfulness: Pope Benedict XVI, in Spe Salvi (§2–3), identifies hope as grounded not in a vague optimism but in a Person who is trustworthy. Verse 24 is perhaps the most compact scriptural expression of this: the one who calls is faithful. The present tense grounds eschatological hope in the permanent character of God. St. John Chrysostom in his homilies on Thessalonians marvels at Paul's audacity: the Apostle does not pray that the Thessalonians will be found worthy, but that God will make them worthy — a profound act of theological confidence in prevenient grace.
On the Parousia: The eschatological framing ("at the coming of our Lord Jesus Christ") connects sanctification directly to the Second Coming, reminding Catholics that holiness is not merely personal improvement but cosmic preparation. Lumen Gentium (§48) teaches that the Church's pilgrim journey is oriented toward the Parousia, and each person's sanctification contributes to the eschatological readiness of the whole Body of Christ.
For contemporary Catholics, these verses offer a corrective to two common errors about the spiritual life. The first is spiritual perfectionism — the anxious, exhausting attempt to sanctify oneself through willpower and discipline, as if holiness were a personal achievement. Paul's prayer places God, not the believer, in the active role. The practical implication: when you fall short — in prayer, in charity, in chastity, in any dimension of the Christian life — the first response is not self-condemnation but renewed surrender to the God of peace who is already at work in you.
The second error is dualism — the unspoken assumption that spiritual life concerns only the soul, and that the body (its rest, its suffering, its pleasure, its vulnerability) is spiritually neutral or even an obstacle. Paul's explicit sanctification of body, soul, and spirit means that what you eat, how you sleep, how you treat physical pain, how you inhabit your sexuality — all of it falls within the scope of God's sanctifying work. Concretely: receive the sacraments, which address the whole person; care for your body as a temple; and let the Eucharist — received bodily — be the privileged instrument of God's "do it" (v. 24).
Commentary